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Alexandra Narin

Healthy Aging and Longevity Research is on the Rise – which is the Best Model Organism to use?

Summary: Humans have been interested in extending our lifespans for centuries, from quests to find the fountain of youth, to Alchemists attempting to determine the formulation for the elixir of life potion, to modern-day dietitians recommending a calorie-restriction and fasting. However, with the advancement of technology researchers are getting a better picture of how, and …

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What happens if the Dietary Supplement Listing Act of 2022 passes? What if it doesn’t?

Summary: This past April, Senators Richard Durbin (D-IL) and Mike Braun (R-IN) introduced the Dietary Supplement Listing Act of 2022. The first piece of legislation to propose regulations for the supplement industry since the Dietary Supplement Health and Education Act of 1994 (DSHEA) was passed, this bill has been met with criticism from both sides: …

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Chemicals Models of Parkinson’s Disease in Larval Zebrafish

Parkinson’s disease [PD] is a progressive, debilitating condition which affects over 10 million people worldwide. Being such an impactful, and costly disease (~$52 billion per year in the USA), researchers have turned to modeling the disease in alternative animal models like the zebrafish (Parkinson’s Foundation, 2018). In this article we discuss how larval zebrafish are …

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If the New Regulation on the Dietary Supplement Industry were to pass, would your Products be Compliant?

Summary: As we have discussed in previous blogs, Dietary Supplements are a booming industry, valued at $54 billion in the USA alone. Despite their growing popularity, however, the USA has comparatively limited regulations surrounding this industry. The dangers of supplements lacking oversight become apparent: for instance, in 2021, Lori McClintock, the wife of U.S. Rep …

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What controls your behavior? Your brain or your gut?

Summary: Over the past decade the microbiome has become known as an important modulator of human health, and research in the field has skyrocketed: publications have risen over 6.2x and clinical trials are up 2.9x. One of the most intriguing areas of research is looking at the link between the microbiome and behavior. While many …

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Review: How a Small Worm is Helping Uncover the Pathogenicity of Gene Variants

We have previously discussed how the advancement of genomics technology has led to an increase in variants of unknown significance (VUS), and how important it is to identify whether or not they are disease-causing. In this review we discuss a recent publication from Dr. Oliver Blacque and collaborators (Lange et al., 2022), where they leveraged …

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Poking its way into Western Medicine: How Acupuncture Could Help Ease Chronic Pain

The Western Medical Community has long viewed acupuncture with skepticism, but increasingly physicians are exploring the potential benefits of this traditional practice. In fact, despite often being referred to as a pseudoscience, recent research has found significant benefits of acupuncture treatment for patients with chronic pain and those suffering from opioid addiction. In this article …

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Testing the efficacy of JadeAging®, a Chinese Medicine based longevity formulation, using InVivo Biosystems’ suite of in vivo platforms

Recently, we have decided to partner with Chenland Nutritionals, Inc., utilizing our suite of in vivo platforms to test the efficacy of their longevity product, JadeAging®. Based on Traditional Chinese Medicine, the formula’s active ingredients are naturally derived: Rehmanniae Radix, Poriae, and Ginseng Radix. In this experiment we will focus on lifespan, healthspan, and transcriptional changes related to aging, and we will document all of it — this article will be the first in a blog-along series where we will walk through our experimental process. So let’s get started!

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