Knock-out and Knock-in technologies enable researchers to modify genes in a chosen model system, and thus, can reveal a lot about how a gene functions. However, while these two methods may sound like complementary opposites, their purpose and design can actually have major differences. In this whitepaper we will discuss the available Knock-out and Knock-in methods, and how they differ, so that you can determine which is best-suited for your experiment.
We discuss the history of two of the most widely studied Cas proteins and how they are shaping the future of research and medicine.
Summary The CRISPR-Cas9 system has become integral in the toolbelts of genomic scientists, researchers, students, etc. Never has it been so easy to wield a pair of molecular scissors in your (pipetting) hand, however, there are a few intracellular processes to consider before cutting up your genome of interest. In this article, we will give …
In this article we compare and contrast several knock-in methodologies. So how do knock-ins work? Continue reading to find out!
Here at InVivo Biosystems we spend a lot of time thinking, and talking, about genome editing. We thought it would be fun to compile a list of our frequently used terms – so here they are, our ABCs of genetic research.
In this white paper we will discuss the advantages and limitations of zebrafish and ask: is a zebrafish model right for my research?
In this whitepaper we discuss the advantages and limitations of C. elegans, and ask the question: is a C. elegans model right for my research?
This article will discuss recent findings, and how similar studies present an exciting and promising future for currently incurable diseases.
In this article we discuss Weissbourd’s recent publication as well as GCaMP more broadly, showing how advancing technology has enabled researchers to ask questions that span disciplines and model organism species.
With knock-in tagging, you can tag your favorite gene at the native locus in your zebrafish line via CRISPR/Cas9 gene editing technology.
