Our Capabilities
InVivo Biosystems was founded based on our expertise in CRISPR genome editing for creating custom genome edited zebrafish and C. elegans.
We have since expanded our CRISPR genome editing platform to create genetic models for therapeutic research to enable faster, cost-effective investigations that focus on proof-of-principle experiments for rapid go/no go decision making.
- CRISPR/Cas9
- Custom Biosensors
- Custom RNAi
- Degron Tagging
- Ectopic Expression
- Extrachromosomal Array Integration
- Fluorescent Tagging
- Floxed Allele/LoxP
- Humanizations
- Immunotagging
- Inducible expression
- Inject Express
- Knockouts
- MosSCI
- Point mutations
- Precise deletion
- RNAi knockdown
- 3xFlag Tag
- Crispant
- CRISPR/Cas9
- CRISPR Injection Mix
- Epitope Tag
- Fluorescent Tagging
- Floxed Allele/Loxp
- Knock-Ins
- Knockouts
- Morpholino
- Point Mutations
- sgRNA validation
- Tol2

C. elegans Behavior & Phenotyping
- Dauer Analysis
- Defecation
- Developmental Lethality
- Egg laying & Fecundity
- Embryo Viability
- Growth Rate
- Imaging
- Lifespan & Healthspan
- Lipid Storage
- Metal Toxicity
- Morphology Analysis
- Movement Analysis
- Oxidative Stress
- Pharyngeal Pumping
- Progeny Production
- RNA interference/knockdown
- Stimulus Preference

Zebrafish Behavior & Phenotyping
- Adult Learning
- Adult Startle Response
- Anxiety
- Birefrengence
- Embryonic Photomotor Responses
- Imaging
- Larval Photomotor Response
- Larval Startle Response
- Microinjections
- Morpholino Injections
- Neurotoxicity
- Pigmentation
- PTZ response
- Shoaling
- Teratogenicity
- Toxicity

Molecular
Analysis
- PCR
- Whole Genome Sequencing
- Whole Transcriptome Sequencing/RNASeq
- inSitu hybridizations

Material
Preparation
- C. elegans Population Expansion
- C. elegans Biobanking
- Large-scale C. elegans Prep

Protein
Labeling
- Western

Computational
Modeling
- Computer vision
- Machine learning models
- Multivariate analysis
- Signal processing
- Statistical hypothesis testing
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